What is Celiac Disease: Types, Causes and Diagnosis
If you want to know about celiac disease, then you have come to the right place. Celiac diseases are getting very popular around the world. According to some reports, 1% of the world’s population is suffering the horrible consequences of this disease, and about 3 million Americans faced the same issues when it comes to its effects and complications for humankind.
We are going to put you at ease in understanding what Celiac Disease is. Celiac diseases are a common disease that arises when you are gluten intolerant and experience damage to the small intestine when you consume gluten. Eating gluten food is extremely dangerous for health, and it is a root cause of several diseases just like this.
Gluten is a collective term for different types of protein that are commonly found in barley, rye, wheat, etc. Gluten-containing grains and products are prevalent in Western counties, especially in their diets. The human body possesses a protease enzyme that helps to digest the protein in the food product. What is the diagnosis?
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History of Celiac Disease
This disease has a long history. About two million years ago, a man developed with almost all the organs. Over time, the man started eating cow, cereals, eggs and got to get the daily protein needs. Celiac disease is generated when some people couldn’t adopt the new foods. Eight thousand years later, Aretaeus of Cappadocia identified and named this disease after having the visible symptoms and appearance of this disease among humankind. He called it “Koiliakos” derived from koelia (abdomen). He narrated that “If the stomach be irretentive of the food and if it passes through undigested and crude, and nothing ascends into the body, we call such person coeliacs.”
Research conducted in 2008 revealed that Samuel Gee gave first presented a clear description of this disease in 1888. He suggested that some dietary changes can be beneficial to get rid of this disease. So, in the late 20th century, countless diets were proposed, but the researchers couldn’t find the actual cause of the disease. The Banana Diet was introduced in 1920 as a dietary treatment. Wim Dicke conducted a study in 1950 to find out which diet change can provide the desired results. He suggested that people who don’t consume wheat, rye, and oats can get rid of this disease, and it can show a considerable improvement as well. Similarly, the study also found the actual cause, i.e., gluten — its earlier studies based on children.
In 1954, Paulley demonstrated the histological abnormalities in the small intestine, and in 1955, Royer conducted various techniques to describe per-oral biopsy. There were countless research and method for this disease over time, and the researchers measured its relativeness to other health conditions. In 1955, Samman suggested that there could be a possible link between the celiac condition and dermatitis herpetiformis while Shuster and Marks established the relationship between 1965 and 1968, respectively. Over time, some societies were developed, such as the Coeliac Society, in 1968. In the 1980s, it also reported the disease can be linked to various health conditions such as diabetes and was accepted as an autoimmune disease in the 1990s. The past studies and experiments helped a lot in a better understanding of the disease. Still, it requires the best treatment to deal with the disease. In the future, there will be an advancement in this regard.
Celiac Disease in Children
The disease has heredity in nature. A child may get infected by parents and second-degree relatives. The symptoms of the disease appear when your child eats food that contains gluten it. A child falls ill after having this disease, so always consider taking the child to a doctor.
For infants, the common symptoms of the disease can be vomiting, bloating, weak growth, irritability, and diarrhea. The signs could be different in school-age children, and they can experience abdominal pain, abdominal distention, constipation, etc.
Celiac Disease Types
There are many types of Celiac disease. This division is based on pain type and linked symptoms. The most prominent examples of this disease are as follows;
As the name suggests, this is the type of illness when you don’t experience any symptoms of the disease but test positive for it. It silently propagates and kills a person who is having it for a long time. The silent type of disease appears by chance when you are going to a doctor for the medication of some other illness. This type of condition can easily be diagnosed by following a strict gluten-free diet. To do so, you need to avoid all the foods that contain gluten. However, leaving the gluten-containing diet menu can be challenging.
Non-responsive is one of the types that continues even when you follow a specific gluten-free diet for a half month to a year. Sometimes, a patient can’t get rid of the disease because gluten may not be the real culprit, or it has been in your body for a very long time and caused significant damage to your body more, especially in your small intestine. Recent studies have shown that more than 25% of the patient found with the non-responsive type of disease. Doctors will prescribe different types of supplements that are gluten-free.
This type of disease happened when you inherited the condition, but no symptoms of the disease show up. In this case, mostly, the visual tests are negative, which means you are not affected by the disease, but this disease eventually develops. It is mostly blood tests that show that it is available or sometimes triggered by other diseases or infections.
It is another type of infection that comes up with clear signs and symptoms. In this case, a person experiences all the symptoms of the disease, such as gas, bloating, and diarrhea, etc. Typical is the type of disease or illness where it affects the small intestine and villi. You can read more here about the symptoms of celiac disease or condition general and read here about symptoms of celiac disease in women.
Celiac Disease Facts and Figures
Celiac disease is widespread these days, and this is why it is crucial to know all the facts and figures about the disease because they are alarming. Let’s have a look at it as now;
- Around the world, 1 in 100 people has celiac disease.
- Around the world, 1 in 56 people has celiac-related symptoms.
- Every 1 in 22 people has celiac whose parents and children (first-degree relatives) are with celiac disease.
- Every 1 in 39 people have celiac whose aunt, uncle, and cousin (second-degree relatives) are with celiac disease.
- About 3 million Americans are affected by celiac disease.
- The average time for the symptoms to show up is about four years, but this time may depend on various other factors.
- Celiac disease is one of the most typical hereditary health problems, impacting about 1% of the world’s population.
- It can affect the organs of your body.
- There are about 300 symptoms of celiac disease.
- It can develop at any stage of life.
Celiac Disease Related Information
- For more Information On Celiac Disease Risk factors: Complications, you can Click Here.
- For more Information On the Symptoms Of Celiac disease in Women, you can Click Here.
What Causes Celiac Disease
Celiac disease is caused by an abnormal immune system reaction towards the gluten protein. The exact celiac disease causes is unknown. Many types of research stated that celiac disease is due to the absence of a gene, which helps in the digestion of gluten-containing food. Without any substantial evidence of exact causes, this disease is complicated to pinpoint its origin.
Signs and Symptoms of Celiac Disease
Celiac disease symptoms and signs fluctuate significantly between children and adults. The following are adult gastrointestinal symptoms and signs or signs of celiac disease:
However, more than half of individuals with celiac disease experience symptoms and signs that are not connected to the digestive tract, such as:
- diarrhea iron deficiency
- Weight loss
- Itchy Rash
- Bloating and gas
- Iron-Deficiency Anemia
- Abdominal pain
- Nausea and vomiting
Most Probable Causes of Celiac Disease
- Infect feeding practices
- Gastrointestinal infections (GIT)
- Gut bacteria
- After surgery
- Viral infection
- Emotional stress
Diagnosis of Celiac Disease
Celiac disease runs in the family. A person who is suffering from this disorder will surely not know that he has celiac disease. If your brother, sister, mother, father, and any other family member have this problem, then you must consult your Doctor and be active to get the test that is most common for celiac disease. Bear in mind that celiac disease is so difficult to detect because of the different types; individuals can have it for a very long time, not knowing they have it. This lengthy harm to the small intestine and digestive system may begin to influence different parts of the body.
Gluten is an environmental trigger, and the central histocompatibility complex area has been identified as a genetic risk factor. Celiac disease is not as uncommon as believed initially, with a global prevalence of roughly 1%. The reason for its under-recognition is due mainly to the fact that approximately half of those affected do not show conventional gastrointestinal symptoms but instead present with nonspecific signs of nutritional inadequacy or have no symptoms at all. The most recent information on the epidemiology, pathophysiology, clinical presentation, diagnostic testing, and therapeutic management of the celiac disease is included in this article.
Diagnosing celiac disease, you need to go through the two following celiac disease diagnosis, which is typical for testing:
1. Serological Test
The presence of certain types of antibodies in the blood indicates that either a person has this abnormality or not. An elevated level of antibodies indicates an immune system’s reaction towards gluten.
2. Genetic Test
This test is the best enough before getting gluten-containing food in your diet. Sometimes your Doctor will demand to get some gluten-containing food in your diet, which gives precise results regarding gluten testing. Antigen HLA- DQ2 and HLA- DQ8 can use for human leukocytes.
A blood test is a more reliable way to diagnose this disorder. The most common blood test is.
- Liver function test
- Complete blood count
- Alkaline phosphatase test
- Cholesterol test
- Serum albumin test
If a person’s results indicated that celiac disease is present, then the Doctor is ready to do more tests for the best outcomes.
- Skin Biopsy
A skin biopsy is another way that your Doctor will prefer to check celiac disease in people with dermatitis herpetiformis. In this, a doctor will remove tinny skin tissues for the microscopic examination with a specific system.
In this test, the Doctor uses a tube. Your Dr. passes a tube from the mouth with a small tiny camera that reaches the small intestine. The camera gives a clear view of the Doctor of your small intestine and makes work easy to get the sample of intestine tissue. The tissue indicates that damage that takes place on villi due to the gluten protein attack. This procedure, also known as a biopsy.
- Capsule Endoscopy
Another way to make sure of the presence of celiac disease. Capsule Endoscopy, a capsule, is available that has a small camera and is sized about the vitamin capsule in which a patient swallow. When that capsule is passing from the GIT, the camera takes many pictures with a clear resolution that are recorded to check the GIT and small intestine conditions.
Curing celiac disease
The current treatment for celiac is a gluten-free diet for life. In most cases, clinical improvement occurs within a few weeks, and mucosal damage heals in 1-2 years. Patients with celiac disease should avoid milk and dairy products during the first phase of treatment. They may have brush border lactase insufficiency due to damage to surface epithelial cells.
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7 Questions to Ask Your Doctor After being Diagnosed With Celiac Disease
Celiac disease is not easy to cure. Once you are diagnosed with celiac disease, mostly there are damages to your small intestine; the gastroenterologist will take samples of your small intestine lining to examine if there are damages to your villi. Your Doctor will be able to give you the information on whether your villi is healthy or severely damaged or moderate.
Then you should ask some questions about your Doctor related to your health condition. Having the right questions to pose to your Doctor at this point will spare you lots of frustrations, time, money, and help you to progress much quicker to a better you. You won’t have many worries again about celiac disease, and you will live a gluten-free life.
1. How Much Damage To The Intestine?
Once you are diagnosed with celiac disease, mostly there are damages to your small intestine; the gastroenterologist will take samples of your small intestine lining to examine if there are damages to your villi. Your Doctor will be able to give you the information on whether your villi is healthy intestinal or badly damaged.
Everybody to remember that damage or harm doesn’t always indicate whether you have severe damage in your small intestine. If your small intestine or villi is severely damaged, your doctor needs to decide if you need further screening for other health problems or not.
2. Should You Go for the Nutritional Deficiency Test?
As a celiac disease patient, in this problem, the malabsorption of nutrients often leads to malnutrition., regardless of whether you were eating a balanced diet. Your symptoms don’t always indicate whether your nutritional status is good or bad, especially if you have most or terrible celiac disease symptoms.
Most of the time, the deficiencies of iron, vitamin D, and vitamins such as folate and B12, calcium, magnesium, and essential fatty acids, etc. are common to the majority of people. This question might prompt your physician to consider testing to determine if you’re deficient in specific nutrients.
3. Is It Necessary To Take The Nutritional Supplements?
When you have celiac disease, your villi are more prone to be damaged, the overall intestinal functioning as well. Physicians usually prescribe their celiac disease patients to take a multivitamin consistently, and medical research supports this. Some physicians may only prescribe supplements that you only have nutritional shortfalls. It all depends on further tests if you have any deficiencies in nutrition. So, ask your doctor this question.
4. Should My Siblings Go Through This Diagnose?
This question is the most important because celiac disease mostly runs in the family. If you have this problem, then surely your sibling might be suffering or likely to suffer from celiac disease. So, always consult with your doctor for the diagnosis of your siblings.
5. Are Dairy Products Still Safe for You to Consume?
In many instances, celiac disease patients can’t endure dairy products that contain lactose; it is a kind of sugar found in milk. The lactose is broken down by an enzyme called lactase, which the intestine’s villi are producing by its tips. If your villi are dissolved or severely damaged by celiac disease, at that point, you can’t make lactase, and lactose digestion won’t be possible.
There are quite many lactose intolerance symptoms out there. The testing can pinpoint whether you are lactose-intolerant or not.
6. Should You Expect Any Future Tests?
Yes, the majority of physicians would recommend future tests to measure antibodies to gluten in your blood. Physicians might recommend either biopsy or endoscopy even after a certain amount of time to check whether your gluten-free diet is overcoming the celiac disease by healing your villi in the small intestine.
7. How do I Correctly Read Food Label?
Yes, it would help to choose the right foods for eating. You must get the knowledge of how you can read the food label? Which is free from gluten protein and does not harm your body. This question will ask your Doctor after the diagnosis.
Treatment for celiac disease
It is an autoimmune disorder in which the human body attacks the small intestine when you consume foods that contain gluten in abundance. Such foods include wheat and rye. During this condition, the body can’t get what it needs from the food you eat.
There is no medication and treatment for celiac disease for now. To avoid this disease, you need to go completely gluten-free. When you visit a doctor, he will refer to a dietician to suggest a perfect gluten-free meal plan. If you strictly follow a gluten-free diet, then you can get rid of this condition over time.
You Need To Just Follow Gluten-Free Diet
As said earlier, there is no proper treatment for this disease. You can hope that the researcher will find the best treatment in the future. However, the best treatment is to go gluten-free for a long time. The average consumption of gluten in food and drinks is only 20 parts per million, which is almost negligible. If you eat foods that contain zero gluten, then it would heal your intestine and bring you back to a healthy lifestyle.
To do so, you need to avoid all the foods that contain wheat by all means. Not only wheat, but you should also avoid the foods that contain gluten. Those foods include rye, barley, farina, malt, and durum. For the perfect meal plan, you need to visit a doctor, and he will suggest you follow a meal plan that will be completely gluten-free. Even a small amount of gluten can be dangerous, so you should be very mindful while eating anything. When buying a product, you need to check the label, whether it is gluten-free or not. Most often, you might be suffering from malnutrition, and you need to supplement it.
Frequency Asked Questions (FAQ)
What is Celiac disease foundation?
It is one of the Foundations with its international efforts to sponsor and implement global initiatives in three main areas to end celiac disease’s suffering: medical research, patient and healthcare provider education, and public policy advocacy.
what are the symptoms of celiac disease?
You can often start to see or notice the symptoms after at least a year on a stringent Gluten-free diet. The following symptoms characterize this Disease:
- Weight loss
- Diarrhea, etc.
These are some symptoms and chronic villous atrophy, confirmed by negative tests results of serology.
Is there a cure for celiac disease?
celiac disease symptoms in adults
You can find more information if you click here.
how is celiac disease diagnosed
You must consult your health practitioner and explain all that you are experiencing. You are sent for the different tests to confirm if you got it or not.
is celiac disease genetic?
Celiac disease is a genetic condition that mostly runs in families. People who have a first-degree family (parent, child, or sibling) who has celiac disease have a one-in-ten likelihood of having celiac disease.
Things You Need To Take Note Of When You Diagnosed With Celiac Disease?
Most dieticians recommend eating oats, but make sure they are labeled as gluten-free. Although you avoid all the wheat, rye, barley, and other products with gluten, it can still be in various medications and products. Such non-food products that contain gluten are lipstick, herbal supplements, food stabilizers, envelope, toothpaste, and vitamins. On the other hand, coffee, pasta, candies, salad, and soups also contain gluten content.
Find Support and Education
Medical follow-up is crucial because it may take about six months for a child and takes several years for an adult. The Doctor may recommend endoscopy and biopsy to check whether the intestine healed. And if it is completely damaged, then he would recommend steroids.
To avoid this disease, you need to be educated and follow whatever the Doctor suggests to you. It is not easy to follow all the medications and gluten-free products for a long time, and people are usually fed up. Join the groups that have like-minded people so that you may get useful suggestions.