Can You Take Omeprazole and Turmeric Together – Recommended dose, interactions, and precautions

Can You Take Omeprazole and Turmeric Together – Recommended dose, interactions, and precautions

An important question is can you take Omeprazole and Turmeric together? Learn how to take Omeprazole and Turmeric together safely, Omeprazole and Turmeric interactions, Omeprazole and Turmeric precautions. Omeprazole is an anti-ulcer medication used to treat stomach acid reflux disease, heartburn, and ulcers. Turmeric contains anti-inflammatory properties that can reduce inflammation of the gastrointestinal tract. However, caution should be taken when combining these medications.

Can you take Omeprazole and Turmeric together?

Can You Take Omeprazole and Turmeric Together

A short answer is no; you cannot take Omeprazole and Turmeric together or simultaneously. It would be best to consider a few things before taking the two together simultaneously. You can take them at different intervals depending on your body’s reaction to each.

A consultation with your medical doctor, nutritionist, or dietician needs to be done first. Based on your body’s reaction to each one of the two and based on those results. They will inform you if it is good for you or not before taking them together. Other people’s body doesn’t even tolerate each or both of them. They are therefore required to use alternative medications.

Turmeric naturally normalizes stomach acid. Turmeric sometimes increases the formation of stomach acid when taken with antacids like Omeprazole.

Omeprazole and Turmeric prevent ulcers, stop gastric emptying, and reduce acid reflux. Omeprazole helps treat drug-resistant heartburn with PPIs.

However, when taking Omeprazole and Turmeric together sometimes causes unwanted reactions. That is why it’s essential to consult your medical doctor first before taking the two together.

When curcumin was administered before ranitidine, there were compensatory effects. The results suggest that mucoadhesion could be the mechanism for wound and gastric ulcer healing. The combinations with bismuth subsalicylate showed an additive effect in both cases, indicating no pharmacologic interaction.

That is why most medical professionals and nutritionists advise that if Turmeric and Omeprazole are taken together, the former may interfere with the action of the latter one. To avoid the interaction, you must take Turmeric and Omeprazole separately with a time interval of at least 3-4 hours.

The primary reason for the possible interference caused by Turmeric in the action of Omeprazole could be the action of curcumin. Several significant reports have reported the likely chances of interaction between Turmeric and Omeprazole. So, it is best to avoid taking Turmeric and Omeprazole together.

You can take Omeprazole (the main ingredient in Prilosec) and Turmeric together to ease stomach problems. Omeprazole is one of the most popular medications for stomach issues, so it’s safe to say that the two work well together.

To know if you should take Omeprazole and Turmeric together, make sure that you’re not allergic or sensitive to them before trying this combination out.

Does Turmeric Interact with Omeprazole

Does Turmeric Interact with Omeprazole?

Yes, Turmeric does interact with Omeprazole. Omeprazole can interact with other nutritional supplements, medicines, or herbal products that you may be about to take or take.

The interactions between herbal remedies and conventional drugs, a pharmacological study is critical because ingesting traditional herbal remedies as supplements or alternative medicine is relatively common worldwide. Their concomitant administration with prescribed drugs could either have a favorable or unfavorable effect, depending on their impact on your body.


How does turmeric interact with the Stomach Acid Production Reducing Drugs (Omeprazole)?

Turmeric usually enhances your Stomach Acid Production, Reducing drugs’ effects such as Omeprazole. When you take Turmeric and Omeprazole together, turmeric enhances the effects of Omeprazole beyond specific actions, resulting in stomach acid production below the standard limit. In this situation, Omeprazole can negatively affect your digestive system instead of promoting ulcer healing.


Medications that interact with Turmeric

  • Warfarin (Coumadin)
  • Metoprolol (Lopressor)
  • Sildenafil (Viagra)
  • Amiodarone (Cordarone)
  • Heparin (Lovenox)
  • Fluconazole (Diflucan)

Note: Turmeric can help lower blood pressure, which Omeprazole helps raise, so it’s possible that taking these two together could cause more risks than benefits.

Medications that interact with Omeprazole

  • Blood-thinning
  • Fungal or yeast infections
  • Anxiety
  • Heart problems
  • Immune suppression
  • Viral infections
  • Epilepsy

The interactions of medicines can modify the form of treatment that interacts with your body. The interactions may lower or increase the effects of the medication, and it may even lead to further harmful consequences.

Turmeric contains curcumin, which has properties that can help decrease inflammation and reduce symptoms of arthritis and psoriasis. For centuries, it has been used in Chinese and Indian traditional medicines to treat many health conditions, including cancer, arthritis, heart disease, diabetes, Alzheimer’s disease, and other medical conditions.

Omeprazole belongs to a group of medicines called proton pump inhibitors. It treats many symptoms like heartburn, ulcers, and gastroesophageal reflux disease (GERD).


What is Turmeric?

Turmeric is known as a spice used in Asian and Indian cooking. This ginger family is a rhizomatous herbaceous perennial plant (Curcuma longa). For centuries, it has been taken as herbal medicine in India and some other countries across Asia to treat different health diseases, including arthritis, diabetes, and cancer.

Recently it has received significant interest from both worlds of medical/scientific, including the culinary world. The medicinal properties of Turmeric, which is the source of curcumin, have been understood for thousands of years; nonetheless, the knowledge to specify the exact mechanism(s) of action and determine the bioactive components have only recently been investigated.

Turmeric has been shown to have antioxidant properties that may assist the prevention of Alzheimer’s disease and other forms of dementia.


Is Turmeric an Anti-Ulcer Agent?

According to animal and human studies reports, Turmeric may be potentially an anti-ulcer agent. So if you take Turmeric and Omeprazole together, Turmeric may enhance the effect of this gastroprotective drug.


Turmeric as an Anti-ulcer agent; from a research perspective

In a recent research study, Turmeric has shown strong gastric acid-reducing properties and enhanced gastric mucus production (protective biomaterial of the gastrointestinal cavity). Turmeric was also found to inhibit pepsin’s activity. The study participants reported a significant improvement in their gastric ulcer healing after consuming turmeric dosages for two consecutive weeks.

In 2011, researchers compared the activity and action of Turmeric and Omeprazole in a research study. The results were astonishing as Turmeric has shown more potency than Omeprazole. Curcumin (the active ingredient of Turmeric) was very effective in preventing gastric lesions’ formation. That was significant proof of the solid anti-ulcer activity of Turmeric.


What is Omeprazole?

Omeprazole is a prescribed medicinal compound that reduces gastric acid production by working as a proton pump inhibitor. When gastric acid production decreases, the risk of gastric ulceration also reduces. Omeprazole is also helpful in the treatment and healing of already present ulcers. It is used as an over-the-counter pill. Commonly, doctors prescribe it for various digestive system-related disorders such as:

  • Peptic ulcers
  • Esophagitis
  • GERD Disease
  • Gastroesophageal reflux disease
  • Zollinger–Ellison syndrome.

It works by blocking the production and action of stomach acid in the body. Omeprazole also inhibits a chemical the secretion of TCTP, which is linked to the consequence of the body’s allergic reaction.


How To Take Turmeric for inflammation

The recommended dose starts mostly between 400-600 mg per day (divided into three doses), but dosages vary depending on your symptoms and other factors like age or physical condition.

Turmeric’s benefits are not limited to just boosting the immune system and reducing joint pain. It also has anti-inflammatory properties, which usually show within a few hours of taking it, which sometimes takes less than that.

You can increase the doses if your body doesn’t react negatively to the Turmeric. You can go all the way to 4000-8000 mg per day (divided into three doses). The amounts you take must not exceed 12,000 mg/day of 95% concentration of the following three curcuminoids without consulting your medical doctor:

  • curcumin
  • Demethoxycurcumin
  • Bisdemethoxycurcumin

It is essential to take note of the concentration of your Turmeric because if you take a too high concentration, you need to take a less amount to prevent adverse effects. If you take a too low concentration, you need to take a high amount to see results.

Take note that one teaspoon of turmeric powder or one teaspoon of ground turmeric is approximately 5000 mg.


Omeprazole dosage for Adults

The form of taking Omeprazole is mainly dependent on the diagnosis of your medical condition, your medical doctor’s recommendation, and the patient’s preference.

  • The scientific recommendation for oral dose to cure symptomatic GERD absent esophageal lesions is mostly 20 mg daily for four weeks. Nonetheless, if erosive lesions are present, Omeprazole may extend treatment to eight weeks.
  • Patients with hypersecretory disorders start the treatment from 60 mg once daily. The treatment is followed by individualizing dosage based on the patient’s requirement and clinical response. If the daily quantity is higher than 80 mg, they should separate the dosage throughout the day. Omeprazole is not recommended for long-term treatment. Instead, switching to an H2-inhibitor is much preferred.

The dosage depends on the child’s weight for pediatric patients between the ages of 1 and 16.

  • A weight that is between 5 to 10 kg: must take 5 mg daily
  • A weight that is between 10 to 20 kg: must take 10 mg daily
  • A weight that is more than 20 kg: must take 20 mg daily

Patients should take Omeprazole at least 30 to 60 minutes before any meal.

You may ingest it with antacids. The first dose is before breakfast and the second before dinner when taken twice daily.

The tablet and capsule should be swallowed as a whole, not to be chewed or crushed. Nonetheless, it is permitted to open the capsule and mix the contents with one tablespoon of applesauce. Until it can be soft enough to be swallowed without chewing, the suspension should be left to thicken for about two to three minutes, following reconstitution and administration within 30 minutes. You can drink with a glass of cool water to confirm the complete swallowing of the pellets.


Precautions should you take while taking Turmeric with Omeprazole

Precautions should you take while taking Turmeric with Omeprazole

Many people who take Turmeric and Omeprazole are unaware that the two substances may react. There is an increased risk of drug resistance or toxic effect of antiretroviral medicines when using Omeprazole.

Omeprazole is assumed as a benign drug; nonetheless, the main adverse results reported in medication labeling include the following:

  • Headache
  • Abdominal pain
  • Nausea
  • Diarrhea
  • Vomiting
  • Flatulence in adults

Long-term and multiple daily dose PPI treatment may have connections with an increased risk for osteoporosis-related fractures of the hip, wrist, or spine. However, newer studies show that long-term PPI use does not correlate with bone mineral density or bone strength changes that would predispose to increased fracture risk, suggesting this relationship is not casual.

Turmeric is considered a blood thinner and shouldn’t be taken together with blood-thinning medications because you might find your blood becoming too thin and weak, which will lead to internal bleeding, nose bleeding, etc.

Scientists encourage diabetes patients not to use Turmeric because it can lower the blood sugar to a too low level. It is best to consult your medical doctor before taking the two medications together.

Curcumin can inhibit the antitumor activity of chemotherapeutics; its use during chemotherapy should only be done under medical supervision. Similarly, vigilance is a must in patients allergic to Turmeric or any of its constituents. Patients allergic to Turmeric should pay equal attention to patients with blood coagulation disorders or under anticoagulants treatment. In these cases, dose adjustments are needed, while patients going for chemotherapy should stop curcumin use in scheduled surgery. Finally, you should apply Turmeric with caution in individuals with diabetes or hypoglycemia or when treated with drugs that lower blood glucose levels.

Turmeric is a natural herb used mainly for inflammation, digestion, joint pains, etc.

Omeprazole is a medication that prevents stomach acid from coming up into the esophagus, managing and treating several conditions, including peptic ulcer disease, etc.

It has been found out through some studies that taking both Turmeric and Omeprazole together can make the absorption of this drug less effective. The best way to prevent this chemical reaction is by taking these two medicines at different times of the day.

Turmeric and curcumin seem to be safely and highly accepted without toxic effects, even in high doses. Moreover, epidemiological data have displayed a few kinds of cancer incidences in individuals who regularly consume curcumin (Aggarwal and Sung, 2009). Nonetheless, the safety of curcumin should be additionally studied, and long-term studies are required for a more helpful evaluation of likely adverse effects and to ultimately determine its harmful possibility.


Advantages of taking Turmeric

Turmeric helps manage oxidative and inflammatory disorders such as:

  • Joint Pain
  • Metabolic syndrome
  • Muscle soreness
  • Anxiety
  • Hyperlipidemia
  • Inflammation
  • Alzheimer disease

You can read more about Turmeric on the following topics:


Disadvantages of taking Turmeric

The disadvantage of taking Turmeric is that some people may have mild side effects such as:

  • Gastrointestinal issues
  • Acid reflux
  • Diarrhea
  • Headache
  • Dizziness
  • Rash
  • Yellow stool


Advantages of taking Omeprazole

PPIs strongly inhibit gastric acid secretion, especially during the daytime after a single daily dose in the morning. Acid suppression is provided orally gradually during the first 3–5 days after starting the drug. PPIs are not tolerable, even after long-term treatment. These characteristics of PPIs can be considered beneficial for the long-term control of gastric acid secretion.

Long-term inhibition of gastric acid secretion is necessary for the maintenance treatment of GERD and the prevention of peptic ulcers with aspirin or NSAID use. Because the acid-suppressing effects of a single dose of PPIs in the morning remain potent during the daytime, PPIs are reported to be effective for preventing recurrence of reflux symptoms and esophageal ulceration/erosion. 19–21 With continued use, GERD recurrence with 1-year maintenance treatment is reported to be less than 15%, while 1-year recurrence without maintenance treatment is estimated to be more than 50%. 24.25 When comparing the preventive effect of PPIs on GERD recurrence with H2RA, PPIs were found to be much more effective.

Long-term administration may also be adequate to prevent the neoplastic conversion of Barrett’s esophagus to dysplastic Barrett’s esophagus, such as adenocarcinoma. It has not been wholly determined whether PPIs effectively suppress dysplastic changes of Barrett’s esophagus. Long-term PPI use was also helpful for preventing recurrence of aspirin-induced peptic ulcers and was more effective than H2RA, with the recurrence rate falling to about 1/10 compared with the placebo-treated group. 23,27–29 Similarly, in cases where NSAIDs were used, PPIs were reported to reduce the recurrence rate to 1/10 compared with the placebo group over a follow-up period of 6 to 12 months.


Disadvantages of taking Omeprazole?

All clinical drugs, including PPIs, have both therapeutic and adverse effects. Most acid inhibition-related adverse effects are observed during long-term PPI treatment, whereas those unrelated to acid inhibition are kept in long-term and short-term PPI users. Some people might experience some of the following:

  • Abdominal pain
  • Muscle spasms
  • Headache
  • Dementia
  • Cerebral ischemic disease
  • Ischemic cardiac disease
  • Chronic kidney disease
  • Acute interstitial nephritis
  • Collagenous colitis
  • Drug allergy
  • Drug interaction with clopidogrel


Can you take Turmeric daily

Yes, but you can take Turmeric daily because it can help with several disorders, including inflammation, arthritis, joint pain, etc.

Take note that taking Turmeric on a daily schedule can also pose the following risks: an allergic reaction such as the following:

  • Difficulty breathing
  • Swelling of the mouth or throat
  • Stomach upset such as:
    • Nausea
    • Diarrhea
    • Constipation
  • Rash
  • Headache
  • Ringing in the ears (tinnitus)

If you plan on taking Turmeric for a long time, you need to start with a minimum dose and not go to a maximum. You also need to consult your medical doctor once you reach four weeks of taking it.


What are the Symptoms of GERD?

The most common symptoms of GERD are as follows:

  • Heartburn
  • Regurgitation
  • Dysphagia
  • Odynophagia
  • Belching
  • Epigastric pain
  • Nausea

Your first action is to consult your medical doctor.


What are the side effects of Omeprazole

Omeprazole has the following side effects:

  • Nausea
  • Diarrhea
  • Constipation
  • Stomach pain
  • Testosterone problems
  • Bloody or cloudy urine
  • Rash or blisters
  • Headache
  • Ringing in the ears (tinnitus)

The following conditions may worsen with a higher dose of Omeprazole:

You need to rush to your medical doctor if you urgently find yourself with these symptoms.


Safest Acid Reflux Medication Over-The-Counter

The FDA’s guide says there are three types of over-the-counter (OTC) medicines available to treat acid reflux or heartburn:

  • Antacids
  • Histamine-2 (H2) blockers
  • Proton pump inhibitors (PPIs)

The stomach releases acid to digest food. But an excessive amount of acid can cause heartburn, peptic ulcers, and even erosion of the esophagus. Antacids help neutralize the excess stomach acid, which helps to reduce these symptoms.

Antacid is a medication that neutralizes excess stomach acid to relieve heartburn and other symptoms caused by indigestion. Antacids are available in both prescription-only and over-the-counter forms. The two main types of antacids are H2 blockers and proton pump inhibitors (PPIs).


H2 blockers work by decreasing the acid produced by the stomach’s parietal cells. This group includes cimetidine (Tagamet), Famotidine (Pepcid), Rizatriptan (Maxalt), and Ranitidine (Zantac).


Proton pump inhibitors are drugs that offer to reduce acid production in the stomach. They contribute to helping in treating various conditions ranging from:

  • Gastroesophageal reflux disease
  • Gastroenteritis
  • Chronic gastrointestinal disorders.

How to use Omeprazole and Turmeric safely and effectively

  1. Please read the label to understand how to take it and all the precautions you must follow.
  2. Taking more than directed or using longer than directed on the label is not permitted, except when advised by your health practitioner.
  3. If your heartburn symptoms continue consistently after using these medications, you need to talk to a healthcare professional quickly.


Can you take Sucralfate and Omeprazole together

The general recommendation for these two medications is not to be taken together due to the risk of increased side effects from their interaction.

Patients should consider that even though the mix may ease their symptoms, it may also raise side effects that might lead to different complications.

The relationship between these medicines is not entirely known. Certain studies have found that Omeprazole is more effective than sucralfate when treating NSAID-induced Gastroduodenal ulcers.


How to take Turmeric as an Anti-Ulcer Agent

The recommended dose for ulcer treatment is usually between 200 mg – 800mg three times a day. The dosages vary depending on many factors, i.e., your symptoms severity and other factors like age or physical condition, etc.

They are many different ways to take your Turmeric, i.e.:

  • With foods
  • With water
  • With smoothie

Most importantly, boiled and roasted curcuminoids improved cell viability, mitigated intracellular accumulation of reactive oxygen species, reduced malondialdehyde activity, reduced caspase-3 and caspase-9 protein expression, and increased superoxide dismutase activity in PC12 cells.

For people who have liver problems or gallstones, Turmeric can cause an increase in bile production, and they should not take Turmeric.

It is clear from studies on Turmeric as an anti-ulcer agent that it has been effective at treating ulcers caused by various factors such as Helicobacter Pylori infection, stomach acid secretion, and injury to stomach lining cells. In some cases, Turmeric seems to be more effective than standard antacids or proton pump inhibitors (PPI).


Can you take Pepcid and Omeprazole together

Yes, you can take Pepcid and Omeprazole together. Although there are not enough studies that show any interactions between the two, that doesn’t mean it is not happening.

It would be best to take them with caution or advice from your health practitioner.


Can you take Mebeverine and Omeprazole together

You can take Mebeverine and Omeprazole together, but not with other drugs like Nurofen, Panadol, or ibuprofen. It is in your best interest to follow the dosage instructions carefully. Mixing the two will cause an erythromycin overdose, leading to serious side effects like renal damage, gastrointestinal discomfort, or hepatic dysfunction.

Not everyone will have the same reaction, and it is always advisable to inform or discuss such information with a health practitioner.


Who should not take Turmeric

Turmeric has many benefits. Some of its uses are in cooking, medicinal purposes, and its anti-inflammatory properties. The active alkaloid in Turmeric is curcumin, and it can be unsafe if you have certain health conditions.

However, some people should not take it because it can cause problems. If you are not certain about whether you should take Turmeric, here is the list of people who should not take Turmeric:

  • People with gallbladder issues
  • People with diabetes
  • People with liver problems
  • People with gallstones or kidney stones
  • Pregnant women
  • Breastfeeding women
  • People ready to go for a surgery
  • People with weak blood or bleeding issues
  • People allergic to curcumin
  • People with low stomach acid levels
  • People with an allergy to Turmeric
  • People with Alzheimer disease

It would be best to consult your medical doctor before using the Turmeric herbal supplement.


What is the best time to take turmeric to get its maximum potency

The best time to take turmeric is after meals. However, according to the experts, taking turmeric before going to bed is the best way to get its maximum potency because it will have time to act in your body through the night. You can mix the turmeric in your food or take it with water or milk.



The information above is crucial for taking precautions while taking turmeric and omeprazole. Side effects that can occur when combining most medicines include an allergic reaction and interactions with other drugs that the person is taking.

When you take omeprazole and turmeric together, you should know the possible side effects and precautions. These include minor stomach discomfort, diarrhea, skin rash, pain in joints or muscles, indigestion, nausea, fatigue, and weakness.

Millions of Americans take prescription drugs daily without consulting their medical professional beforehand. We all know that it is imperative to speak with a doctor before taking any medication, but millions of us forget to do so, which can be life-threatening.


Lucky Thomo

Welcome to – a blog that focuses on spreading the healthy way of living and saving money in the process. My name is Lucky Thomo and I’m currently employed full time and do Blogging part-time, wishing to go blogging full-time in the future. I'm more into health and fitness with this website. I do research in my spare time and also introduced the way of living and eating into my family. In 2019 I stumbled upon a YouTube Video about ‘Blogging’. I was skeptical at first because there are too many scams out there. I was given a free 7 (Seven) days no question's asked if I want to cancel. I start a personal blog on the free seven days where I’ve gone deeper into the Healthy and Fitness industry. After that free seven days, I decided to go on and paid to continue with the programs because I saw value in the platform. I continued like that ever since. I’ve learned many things from the experience of the platform that I joined. My blogs are growing steadily in popularity and authority. I started as a hobby but now I enjoy it more than before. I am slowly building my blogging into an income source that will enable me to dedicate more and more time to it and eventually become a full-time blogger. To find out more about my story, you can read it in the tab "About Lucky" on my website. You can also visit my blog post to have a look at my work.

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